BPC-157 Dosage Guide: How Much Should You Take? (2026)

Key Takeaways

• Standard Dosage Range: BPC-157 is typically administered in doses ranging from 200 mcg to 500 mcg per day, depending on the form and therapeutic goal.
• Administration Method: The most common route is subcutaneous injection, though oral and topical forms are also used.
• Typical Cycle Length: Treatment cycles generally last between 4 to 12 weeks, with some protocols suggesting a tapering phase.
• Regulatory Status: BPC-157 is classified as a Category 2 peptide, prohibited by the FDA for human use outside of research settings.
• Medical Supervision: Due to regulatory status and potential side effects, BPC-157 should only be used under the guidance of a licensed healthcare provider.

How BPC-157 Works in the Body

BPC-157, a synthetic fragment of a protein found in gastric juice, is known for its potential in tissue repair and recovery. Its mechanism of action involves promoting angiogenesis, modulating growth factor production, and enhancing cellular repair processes. The peptide binds to receptors in the body, initiating a cascade of healing processes.

The half-life of BPC-157 is relatively short, necessitating frequent dosing to maintain therapeutic levels. Its bioavailability varies significantly depending on the administration route. Subcutaneous injections are preferred for their direct delivery into systemic circulation, whereas oral administration may result in reduced bioavailability due to digestive breakdown.

"BPC-157 has demonstrated pleiotropic beneficial effects in various preclinical models mimicking medical conditions, such as tissue injury and inflammatory bowel disease." — PMID 40005999

"The peptide's stability and interaction with molecular pathways make it a promising candidate for cytoprotection and healing." — PMID 36359218

Standard BPC-157 Dosage Ranges (By Form)

Subcutaneous Injection

• Dosage Range: 200 mcg to 500 mcg per day
• Frequency: Once daily or split into two doses
• Bioavailability: High, with direct systemic absorption
• Commonality: Preferred for its efficacy and ease of administration

Oral Administration

• Dosage Range: 500 mcg to 1,000 mcg per day
• Frequency: Once daily
• Bioavailability: Lower due to digestive processes
• Use Case: Often used for gastrointestinal issues

Topical Application

• Dosage Range: Variable, depending on the formulation
• Frequency: As directed, usually twice daily
• Bioavailability: Localized effect with minimal systemic absorption
• Use Case: Primarily for skin and surface-level tissue repair

BPC-157 Dosage by Use Case

Tissue Repair and Recovery

• Typical Dosage: 250 mcg to 500 mcg daily
• Administration: Subcutaneous injection
• Cycle Length: 6 to 12 weeks
• Clinical Reference: Many clinics report positive outcomes in tissue healing with this protocol.

Gastrointestinal Health

• Typical Dosage: 500 mcg to 1,000 mcg orally
• Administration: Oral
• Cycle Length: 4 to 8 weeks
• Clinical Reference: Studies suggest improved gut health and reduced inflammation (PMID 40005999).

Musculoskeletal Injuries

• Typical Dosage: 200 mcg to 400 mcg daily
• Administration: Subcutaneous injection
• Cycle Length: 8 weeks
• Clinical Reference: Enhanced soft tissue healing observed in preclinical models (PMID 30915550).

How Long Should You Take BPC-157?

The duration of BPC-157 therapy varies based on the therapeutic goal and individual response. Typical cycles range from 4 to 12 weeks, with some protocols recommending a gradual tapering to minimize withdrawal effects. Continuous use beyond recommended cycles is not advised due to the lack of long-term safety data.

During the initial weeks, patients may notice subtle improvements, with more pronounced effects typically emerging by week 4 to 6. If treatment is discontinued, some regression of benefits may occur, necessitating periodic reassessment by a healthcare provider.

Administration Protocol: How to Take BPC-157

Injection Technique

• Needle Gauge: 29 to 31 gauge for subcutaneous injections
• Injection Sites: Rotate between abdomen, thigh, and upper arm
• Rotation Schedule: Change sites daily to prevent tissue irritation

Oral Administration Timing

• Timing: Best taken on an empty stomach to enhance absorption

Storage Requirements

• Temperature: Store at 2-8°C (36-46°F)
• Light Sensitivity: Protect from direct sunlight
• Reconstituted Stability: Use within 14 days when refrigerated

Reconstitution Instructions

• Guide: See our reconstitution guide for detailed steps

Step-by-Step Administration

1. Preparation: Wash hands and clean the injection site with alcohol.
2. Reconstitution: Mix BPC-157 with bacteriostatic water if supplied as a powder.
3. Drawing: Use a sterile syringe to draw the reconstituted solution.
4. Injection: Administer subcutaneously at the chosen site, rotating locations daily.
5. Disposal: Safely dispose of needles in a sharps container.

Stacking BPC-157 for Better Results

BPC-157 and TB-500

• Combination: BPC-157 with TB-500 for enhanced tissue repair
• Dosing Synergy: 250 mcg BPC-157 with 2 mg TB-500 weekly
• Protocol: Commonly used in the "Wolverine protocol" for rapid recovery

BPC-157 and CJC-1295

• Combination: For muscle growth and recovery
• Dosing Synergy: 300 mcg BPC-157 with 100 mcg CJC-1295 daily
• Protocol: Used in athlete recovery programs

Factors That Affect Your BPC-157 Dosage

Several factors influence the optimal dosage of BPC-157, including body weight, age, specific treatment goals, and individual physiological responses. Providers may adjust dosing based on these variables to maximize efficacy and minimize risks.

• Body Weight: Heavier individuals may require higher doses for the same therapeutic effect.
• Age: Older patients may metabolize peptides differently, warranting adjustments.
• Health Status: Conditions affecting liver or kidney function can alter peptide clearance rates.

Common Dosing Mistakes to Avoid

• Dosing Too High/Too Low: Stick to recommended ranges to avoid side effects or insufficient efficacy.
• Inconsistent Timing: Maintain a consistent schedule to ensure stable peptide levels.
• Wrong Injection Site: Use appropriate sites to maximize absorption and minimize irritation.
• Regulatory Compliance: Be aware of BPC-157's prohibited status and seek professional guidance.
• Improper Storage: Store correctly to preserve peptide stability and effectiveness.

What the Evidence Does Not Show

While BPC-157 shows promise in preclinical models, significant gaps remain in human clinical data. Long-term safety and efficacy studies are lacking, and most evidence comes from animal studies or anecdotal reports. This limits the ability to make definitive conclusions about its therapeutic potential in humans.

FAQ — Your Top BPC-157 Dosage Questions Answered

Best time of day to take it?

BPC-157 can be taken at any time but should be administered consistently at the same time each day.

What if you miss a dose?

If you miss a dose, take it as soon as you remember unless it's close to the next scheduled dose. Do not double up.

Can men and women use the same dose?

Yes, dosing is generally based on therapeutic need and weight, not gender.

Can you stack it with other peptides?

Yes, BPC-157 is often stacked with peptides like TB-500 and CJC-1295 for synergistic effects.

How long until you see results?

Many patients report improvements within 4 to 6 weeks, though this varies.

Do you need to cycle off?

Cycling off is recommended to prevent potential desensitization and to evaluate ongoing need.

Is a loading dose needed?

A loading dose is not typically required for BPC-157.

How to adjust dose if side effects occur?

If side effects occur, consult your provider to adjust the dosage or discontinue use.

Conclusion — Finding the Right Dosage for You

Determining the correct dosage of BPC-157 involves considering multiple factors, including therapeutic goals and individual responses. Always consult with a healthcare provider before starting peptide therapy to ensure safe and effective use. For more information, visit our BPC-157 encyclopedia page and use our clinic finder to locate a qualified provider near you.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Dosage information is compiled from published research and clinical protocols. Consult a licensed healthcare provider before starting any peptide therapy. Use our clinic finder to locate a qualified provider near you.