PeptideClinicLocatorOverview
NAD+ (nicotinamide adenine dinucleotide) is an essential coenzyme involved in cellular energy production, DNA repair, and numerous metabolic pathways. It is technically not a peptide but is commonly grouped with peptide and longevity therapies. NAD+ can be legally compounded in the US—it meets the criteria (e.g., GRAS-related pathway). People use it for cellular energy, anti-aging, addiction recovery, neuroprotection, and cognitive enhancement. Administration can be IV infusion, subcutaneous injection, or oral/sublingual supplements. Evidence is moderate and growing, with a particular body of human work around IV NAD+ for certain conditions. It is one of the few “longevity” compounds with a clear legal compounding path.
How It Works (Mechanism of Action)
NAD+ is a cofactor for enzymes involved in glycolysis, the Krebs cycle, and sirtuin activity. Declining NAD+ with age is thought to contribute to metabolic and cellular dysfunction. Supplementing NAD+ (or precursors) may support cellular function and energy metabolism. IV delivery bypasses absorption limits of oral forms.
