PeptideClinicLocatorOverview
GHRP-2 is a growth hormone releasing peptide that stimulates GH release and can increase appetite. It has been used for GH support and anti-aging. Regulatory status is complex: it is Category 3 on the 503A list but Category 1 on the 503B list for non-injectable and non-nasal routes only. So injectable GHRP-2 is not permitted under the 503B Category 1 pathway. Patients and pharmacies must ensure that any use complies with the route-specific restrictions. Evidence is moderate—some human studies. For straightforward legal GH support, sermorelin remains the clearer option.
How It Works (Mechanism of Action)
GHRP-2 activates receptors that stimulate growth hormone release. It can also increase appetite, which may be desirable or undesirable depending on goals. It is typically used by injection in practice, but that route is not on the 503B Category 1 list.
Primary Uses
Marketed for GH stimulation, appetite increase, and anti-aging. Evidence moderate. Injectable use not on 503B Category 1.
FDA & Regulatory Status
Complex. Category 3 on 503A. Category 1 on 503B for NON-INJECTABLE and NON-NASAL routes only. Injectable use is not permitted under 503B Category 1.
Last reviewed February 2026.
