PeptideClinicLocatorOverview
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied in Russian research (e.g., Khavinson) for telomerase activation, anti-aging, and circadian rhythm regulation. It is not FDA-approved and has no compounding pathway in the US—it has not been FDA-evaluated. Evidence is emerging and primarily from Russian research, with limited Western validation. It is prohibited for compounding. People interested in evidence-based longevity approaches should look to FDA-approved or legally compoundable options and well-validated lifestyle and medical interventions.
How It Works (Mechanism of Action)
Proposed mechanisms include telomerase modulation and effects on circadian regulation. Most data are from non-US research; mechanisms in humans are not established in the US regulatory or scientific mainstream.
Primary Uses
Marketed for telomerase activation, anti-aging, and circadian rhythm. Not legal in the US. Evidence emerging, primarily Russian research.
FDA & Regulatory Status
Prohibited for compounding. No pathway; not FDA-evaluated.
Last reviewed February 2026.
Clinical Evidence
Emerging—primarily Russian research (Khavinson), limited Western validation.
